Lutein and Zeaxanthin For Healthy Eyes. Dietary Supplements:Vitaminized. Diet supplements that work

BENEFITS OF LUTEIN AND ZEAXANTHIN SUPPLEMENTATION IN PATIENTS WITH DIABETIC RETINOPATHY

Retinopathies are characterized by inflammation and vascular remodeling and may be caused by systemic disorders. One such disorder is diabetes, which may result in the development of diabetic retinopathy, which affects >8,000 individuals in the USA each year and accounts for 12% of new cases of blindness [1]...

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BENEFITS OF LUTEIN AND ZEAXANTHIN INTAKE IN PATIENTS WITH AGE-RELATED MACULAR DEGENERATION, RETINITIS PIGMENTOSA AND CATARACTS

Oxidative stress is well known to contribute to the onset and progression of a number of eye diseases, including at least some forms of retinal degeneration, particularly age-related macular degeneration (AMD) [1], which is the most common cause of blindness in developed countries...

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BENEFITS OF TAKING ZEALUT-DENA (LUTEIN AND ZEAXANTHIN) FOR PATIENTS WITH RETINITIS PIGMENTOSA

Retinitis pigmentosa is a heterogenous group of hereditary conditions that lead to gradual retinal degeneration that results from progressive loss of rod and cone photoreceptor cells and results in the loss of night vision (provided by rod photoreceptor neurons) in adolescents, followed by the loss of side vision in young adults (which causes so-called "tunnel vision"), and finally by the loss of central vision (high-acuity daylight vision, provided by cone photoreceptors) [1, 2]. Despite similar disease progression, the etiology of retinitis pigmentosa is different in different patients, with causative mutations identified in >45 genes [1]. However, in many patients, the exact causes of the disease remain unknown...

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BENEFITS OF ZEALUT-DENA (LUTEIN AND ZEAXANTHIN) IN SUBJECTS WITH COMPUTER VISION SYNDROME

According to a survey conducted more than a decade ago, more than half of the working population used computers at that time [1], and the proportion of people using various electronic screens for work and in everyday life is thought to be now close to 100% [2]. It has long been recognized that prolonged use of electronic screens results in a variety of visual symptoms in a considerable proportion of users (56%, range 25%–93%, according to a review of nine studies published between 1974 and 19933, or 64–90% according to a more recent review [2]). The reported symptoms include eyestrain, headaches, ocular discomfort, dry eye, diplopia (double vision) and blurred vision. Taken together, these symptoms are referred to as computer vision syndrome (CVS). Some authors consider CVS to be synonymous with asthenopia [4], whereas others consider asthenopia synonymous with eyestrain and thus one of the symptoms of CVS. Regardless of the definition, eye- strain (or asthenopia in the narrow sense) is the main parameter used to quantitate the prevalence of CVS [5]...

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POTENTIAL BENEFITS OF ZEALUT-DENA (LUTEIN AND ZEAXANTHIN) IN INDIVIDUALS EXPOSED TO BRIGHT LIGHT

Excessive light is known to damage the retina [1], in particular by inducing apoptosis (cell death) of photoreceptor cells [2] and causing complex post-exposure retinal remodeling, which eventually becomes irreversible [3]. Excessive light is particularly damaging in patients with degenerative retinal diseases because it synergistically accelerates photoreceptor cell death [3]. Damage caused by bright light and by these diseases may involve similar mechanisms, because late-stage retinal remodeling after light damage is similar to the anatomical changes observed in advanced age-related macular degeneration (AMD) [4]. Collectively, retinal damage from bright light is known as solar retinopathy, or solar retinitis, regardless of whether it is caused by sunlight or an artificial source of bright light, such as welding arc [5]...

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BENEFITS OF ZEALUT-DENA (LUTEIN AND ZEAXANTHIN) INTAKE IN SUBJECTS AT RISK OF CATARACT DEVELOPMENT

Oxidative stress is known to contribute to the onset and progression of a number of eye diseases [1]. Cataracts, along with age-related macular degeneration, are a major cause of blindness in the elderly. Oxidative stress, especially that caused by UV light, plays an important role in cataract development by promoting oxidation of lens proteins [2, 3]. The carotenoids lutein and zeaxanthin are thought have a dual protective effect: they filter out the most damaging short-wavelength irradiation (blue light and UV) and scavenge reactive oxygen species. Although most lutein and zeaxanthin in the eye is concentrated in the retina (especially in the macula), they are the only carotenoid species present in the lens [4, 5]. Over the last ~30 years, a number of studies have been conducted to determine whether lutein and zeaxanthin may reduce the risk of age-related cataracts...

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